What Is
Vaginal
Estrogen?
What You Put Into Your
Body Matters.
Vaginal estrogen is the most effective treatment for symptoms of vulvar and vaginal atrophy caused by menopause.

Because it addresses estrogen loss, the root of the problem, you can treat the cause of painful sex during menopause.
That’s why we’ve designed IMVEXXY to be a bio-identical, localized estrogen in ultra-low dose.*
BIO-IDENTICAL
Bio-identical is just a way of saying it was made to mimic your body’s
own estrogen.*
*Bio-identical hormones are hormones that are structurally identical to the hormones your body produces naturally. It is not known if there is a difference in risks between synthetic hormones and bio-identical hormones.
LOCALIZED
Because IMVEXXY is inserted directly into your vagina, the estrogen works where it’s actually needed. Localized therapy (like an insert) actually has fewer risks associated with it than what we call systemic therapy (an oral pill), although estrogen levels are different in each therapy and have different risks and product profiles.*
*The clinical relevance of systemic absorption rates for all vaginal estrogen therapies is not known. Systemic absorption may occur with IMVEXXY. The risks associated with systemic estrogen therapy should be considered.
ULTRA LOW DOSE
If you’re thinking about starting estrogen, choose IMVEXXY, which is the ONLY ultra-low dose option in a softgel insert—in fact, it’s the lowest dose vaginal estrogen out there. Taking IMVEXXY for one year is less estrogenic than taking a single average birth control pill. Of course, oral birth control is different than a vaginal estrogen softgel like IMVEXXY. Each use of estrogen is different and has different risks and product profiles.